Search results for "Hormones esteroides"
showing 4 items of 4 documents
The maternal hormone in the male brain: Sexually dimorphic distribution of prolactin signalling in the mouse brain.
2018
Research of the central actions of prolactin is highly focused on females, but this hormone has also documented roles in male physiology and behaviour. Here, we provide the first description of the pattern of prolactin-derived signalling in the male mouse brain, employing the immunostaining of phosphorylated signal transducer and activator of transcription 5 (pSTAT5) after exogenous prolactin administration. Next, we explore possible sexually dimorphic differences by comparing pSTAT5 immunoreactivity in prolactin-supplemented males and females. We also assess the role of testosterone in the regulation of central prolactin signalling in males by comparing intact with castrated prolactin-supp…
Effects of Estrogen on Vascular Inflammation
2012
Objective— Our study aims to determine the role of time of menopause on vascular inflammation biomarkers and how it affects their modulation by estrogen and raloxifene in postmenopausal women. Methods and Results— Uterine arteries from 68 postmenopausal women were divided into 3 segments and cultured for 24 hours in tissue culture media containing 17β-estradiol (100 nmol/L), raloxifene (100 nmol/L), or vehicle. Assessment of arterial concentration of 13 inflammatory biomarkers was performed by multiplex immunobead-based assay. Aging per se has a positive correlation with the generation of several proinflammatory markers. Although short-term estradiol exposure correlates with lower expressi…
The epidemiology of anabolic-androgenic steroids use among secondary students (Valencia-Spain)
2019
The consumption of anabolic-androgenic steroids (AAS) is continuously growing in recent years among young people. The purpose of the current study was to examine the proportion of students who reported AAS use, explore other drug use among them and finally to determine the sociodemographic profile of the AAS consumption amongst a sample of students in the Valencian Region (Spain). Method. Data was taken from a self-administrated survey of a representative sample of 1,1162 Valencian students. A total of 252 schools participated in the study. Results. The findings show that 3.3% of surveyed students reported that they had consumed AAS. Males reported to take anabolic more frequently than fema…
Anabolic steroids and their effects on health: a case study of media social responsibility
2019
Anabolic steroids are among the oldest performance- enhancing drugs in sport and their use has spread into many other layers of society. The use and sale of steroids are illegal in most parts of the world, and authorities who attempt to combat trafficking in them find themselves engaged in ceaseless, yet ultimately futile efforts: traffickers are always a step ahead of them. However, an effective way to combat steroid use could be to inform people about these drugs' advantages and disadvantages. The mainstream media can play an important part in this process. They have a social responsibility to provide exhaustive information about the long-term damage caused by these substances. Do journal…